Course Outline: Biophotonics

BME 410/ OPSE 410, Fall 2001

Instructors: J. F. Federici, Office: 474T, x8482; email: federici@adm.njit.edu

TA's: Kakhkhor Adbijalilou, email: kxa9305@njit.edu

Office Hours: Federici: Mon. 11:30-1:00pm or by appointment.

Course Materials: "" by S. Rastegar and G. Cote, Chapter 17 in Introduction to Biomedical Engineering; Instructor handouts distributed via class Web page.

Note: The laboratory manual will be distributed in class or via the World Wide Web. OPSE web address: physics.njit.edu/~federici , or www.njit.edu/Directory/Centers/OPSE

OPSE Lab Open Hours: OPSE lab (642-4956) will be open during Monday 11:30-1pm and Weds. 2:30-4pm or by appointment.

Prerequisites: Phys 121

Assignments: You are responsible for all weekly reading and laboratory assignments listed in this outline. The reading should be completed BEFORE class each week. Laboratory assignments must be turned in BEFORE at the beginning of class each week. All assignments (if you prefer) may be submitted via an attached email to federici@adm.njit.edu. You may WINZIP the files if necessary. Any files that are infected with a virus will not be accepted.

Exams: Midterm and Final Exams will be given. Each exam will consist of homework type problems as well as laboratory practical questions.

Grades: Midterm Exam and Final Exam each count as 3/16 of grade. Laboratory Reports collectively count as 1/2. Homework counts as 1/8 of the final grade. Grades of below 50% will generally considered to be failing.

Syllabus

Week Topic Lab Assignment Reading Assignments and HW
1 Interaction of Light with Bio Tissues - Overview

Basics of Light Propagation

Lab 1 Chap. 17.1-17.2.3, Exercise 3;
HW Sheet 1 (do problems 2.2, 2.4, 2.6, 3.12, 3.14, 3.33)

Solutions: HW Sheet 1 (PDF), Exercise 3 (PDF)

2 Absorption - Beer's Law Lab 2 or Lab 3

Lab 2 (PDF)

Lab 3 (PDF)

Chap. 17.3-17.3.2, 17.5-17.5.1,
Exercise 13

Ex 13 Solution (PDF)

3 Scattering of light - Theory Lab 2/3 (cont) Chap. 17.5.2-17.5.3, Exercise 17;
HW Sheet 2

NOTE: on Exercise 17:

Exercise 17 Solution

4 Scattering of Light TBA
5 Measurement of Tissue Absorption and Scattering - Integrating Spheres Lab 4 (WORD)

Lab 4 (PDF)

Integrating Sphere Manual

HW-IAD program (WORD)

IAD program (EXE file)
Sample Input file
Directions

6 Integrating Spheres Lab 4
7 Fiber-Optics and Endoscopy Lab 8 (WORD)

Lab 8 (PDF)

Chap. 17.7, Exercise 1

MIDTERM

Midterm Solutions

8 Fiber-Optics and Endoscopy lab 8 (cont)
9 Polarization and birefringence - Theory Lab 6 (WORD)

Lab 6 (PDF)

Chap. 17.5.4
Exercise 12

Ex 12 Solutions

10 Polarization and Birefringence Lab 6 (cont) Exercise 4

Exercise 4 Solutions

11 Basics of Laser Surgery - Theory Lab 5 Chap. 17.6
NSF press release and Video
Biophotonics article
12 Laser Surgery Lab 5 Ex. 5,6,7

Ex 5,6,7 Solutions

13 Exercise 14, 15, 16, 18

Ex 14, 15, 16, 18 Solutions

14 Simulation of light Propagation in Tissues Lab 7 HW

 

Lab Number

Topic

1

Photonics Laboratory Basics - Mirrors, lasers, and alignment

2

Absorption of Light - Beer's Law

3

Scattering of Light

4

Integrating Sphere - Scattering and Absorption in a Turbid Medium

5

Simulated Laser Surgery

6

Polarization and Chiral Molecules

7

Monte Carlo Simulations of Light Propagation in Turbid Medium

8

Fiber-Optics and Endoscopy