Office of the President

IMPROVING MICROSCOPY

Mathematical and experimental modeling of immunocolloid labeling techniques for electron microscopy is the focus of research by Christopher S. Raymond, assistant professor of mathematical sciences. Immunocolloid labeling is a technique that allows biomolecules to be labeled so that they can be detected using an electron microscope.

Dr. Raymond's goal is to develop mathematical models for the process that will then show the best way to choose the conditions under which the labeling is performed. The goal is to find the balance in which labeling can be attached to as many molecules as possible, while minimizing the number of molecules that get labeled erroneously as well as the time required for the process. He is collaborating with mathematicians at the University of Wisconsin and the University of Delaware on the modeling component of the project, and with the electron microscopy group at the University of Wisconsin to test the mathematical models against experiments.